ACCAL (Algarve Charity for Children and Families): Supports local families in need, particularly focusing on children's welfare. 

C.A.S.A. (Homeless Support Centre): Active in several Algarve cities, providing meals and basic necessities to the homeless. 

Madrugada Association: Provides palliative care and support for people with life-limiting illnesses in the Western Algarve.

APAV (Victim Support Association): Offers free and confidential support to victims of crime and domestic violence. 

Castelo de Sonhos (Castle of Dreams): A Silves-based charity helping the underprivileged and elderly with food and social support. 

afpop (Association for Foreign Residents and Property Owners): The largest association for expats, providing legal, financial, and practical advice. 

Association of Ukrainians in the Algarve: Provides support for the Ukrainian community and organizes cultural integration events. 

• Alliance Française de l'Algarve: Promotes French language and culture through events and classes.

ARA (Animal Rescue Algarve): A state-of-the-art shelter near Loulé focused on rescue and adoption.

Tiny Shelter Albufeira: A non-profit dedicated to rescuing abandoned dogs and finding them forever homes. 

Street Cats Algarve: Focuses on the sterilization and care of feline colonies across the region. 

Almargem: The primary association for the defense of the Algarve's cultural and environmental heritage (Via Algarviana). 

A Rocha Portugal: A Christian-based environmental organization focused on bird research and nature conservation in Alvor.

ACTA (Algarve Theatre Company): Based in Faro, it is the main professional theatre group in the region. 

NERA (Algarve Business Association): The largest regional association supporting local companies, innovation, and training. 

ACRAL (Algarve Trade & Services Association): Represents the retail and service sectors, focusing on local commerce development. 

Algarve Business Network: An international community for entrepreneurs, digital nomads, and business owners living in the Algarve. 

AA (Alcoholics Anonymous) Algarve: Probably the most active international network in the region. They hold frequent English-speaking meetings in Lagos, Almancil, Tavira, and Albufeira.

NA (Narcotics Anonymous): Support groups for those struggling with drug addiction, following the 12-step program with meetings across the Algarve. 

Al-Anon Algarve: Specifically for the families and friends of alcoholics, helping them cope with the impact of a loved one's addiction.

Gamblers Anonymous (Jogadores Anónimos): Support for those struggling with compulsive gambling, a service often sought after in regions with casinos. 

Projecto Homem (Faro): A well-known NGO that provides rehabilitation programs and therapeutic communities for various types of dependencies.

ASMAL (Algarve Mental Health Association): Focuses on the rehabilitation and social integration of people with psychiatric disorders, which often overlap with addiction. 

GATO (Group of Help for Drug Addicts): Based in Faro and Portimão, they offer social support and harm reduction programs.